Rare Diseases and Orphan Drugs shows that much of what we now know about common diseases has been achieved by studying rare diseases. It proposes that future advances in the prevention, diagnosis, and treatment of common diseases will come as a consequence of our accelerating progress in the field of rare diseases. Understanding the complex steps in the development of common diseases, such as cancer, cardiovascular disease, and metabolic diseases, has proven a difficult problem.

Rare diseases...

The Craft and Science of Coffee follows the coffee plant from its origins in East Africa to its current role as a global product that influences millions of lives though sustainable development, economics, and consumer desire. For most, coffee is a beloved beverage. However, for some it is also an object of scientifically study, and for others it is approached as a craft, both building on skills and experience.

By combining the research and insights of the scientific community and expertise o...

Encyclopedia of Cancer, Third Edition, provides a comprehensive, up-to-date overview of the multiple facets of the disease, including research, treatment and societal impact. This new edition comprises 180 contributions from renown experts who present the latest in Mechanisms, Hallmarks of Cancer, Causes of Cancer, Prevention and Control, Diagnosis and Therapy, Pathology and the Genetics of specific Cancers. Readers will find a comprehensive overview of the main areas of oncology, including e...

Handbook on Animal-Assisted Therapy: Foundations and Guidelines for Animal-Assisted Interventions, Fifth Edition highlights advances in the field, with seven new chapters and revisions to over 75% of the material. This book will help therapists discover the benefits of incorporating animal assisted therapy into their practice, how to design and implement animal assisted interventions, and the efficacy of animal assisted therapy with different disorders and patient populations. Coverage includ...

Comprehensive Structural Integrity, Second Edition, a Ten Volume Set, provides material scientists and engineers with an authoritative and complete one-stop reference tool on all aspects of this exciting field. The book puts special emphasis on the interaction between mechanics and materials and structural integrity applications. Because of the interdisciplinary and applied nature of the work, it is an indispensable resource for mechanical engineers and materials scientists from both academic...

There have been two main traditions of writing on ethics in the Islamic tradition, one philosophical and related to the works of Aristotle and other Greek philosophers, represented by thinkers such as Avicenna, and one theological, represented by such figures as the famous theologian al-Qadi Abd al-Jabbar. Some later scholars attempted to combine those two traditions. For the most part, however, the views of the jurists have been ignored.

Abdulaziz Sachedina herecalls attention to this third ...

Discover the secrets of world-class leadership!When it comes to refined service and exquisite hospitality, one name stands high above the rest: The Ritz-Carlton Hotel Company. With ceaseless attention to every luxurious detail, the company has set the bar for creating memorable customer experiences in world-class settings. Now, for the first time, the leadership secrets behind the company's extraordinary success are revealed.

The New Gold Standard takes you on an exclusive tour behind the sce...

A must read for any HR executive. This research-based competency model is particularly compelling because it is informed by the perspective of non-HR executives and stakeholders.

The new C++11 standard allows programmers to express ideas more clearly, simply, and directly, and to write faster, more efficient code. Bjarne Stroustrup, the designer and original implementer of C++, has reorganized, extended, and completely rewritten his definitive reference and tutorial for programmers who want to use C++ most effectively. The C++ Programming Language, Fourth Edition, delivers meticulous, richly explained, and integrated coverage of the entire language—its facilities, a...

Now in its 7th edition, Auerbach's Wilderness Medicine continues to help you quickly and decisively manage medical emergencies encountered in any wilderness or other austere setting! World-renowned authority Dr. Paul Auerbach and 2 new associate editors have assembled a team of experts to offer proven, practical, visual guidance for effectively diagnosing and treating the full range of issues that can occur in situations where time and resources are scarce. Now in an exciting 2-volume set tha...