Building upon the success of best-sellers The Clean Coder and Clean Code, legendary software craftsman Robert C. "Uncle Bob" Martin shows how to bring greater professionalism and discipline to application architecture and design. As with his other books, Martin's Clean Architecture doesn't merely present multiple choices and options, and say "use your best judgment": it tells you what choices to make, and why those choices are critical to your success.

Martin offers direct, no-nonsense answer...

Now in its tenth edition, the Oxford Handbook of Clinical Medicine has been fully revised, with five new authors on the writing team bringing content fresh from the bedside. Space has been breathed into the design, with more core material at your fingertips in quick-reference lists and flow diagrams, and key references have been honed to the most up-to-date and relevant. Each page has been updated to reflect the latest changes in practice and best management, and the chapters on gastroenterol...

Biopharmaceutical Processing: Development, Design, and Implementation of Manufacturing Processes covers bioprocessing from cell line development to bulk drug substances. The methods and strategies described are essential learning for every scientist, engineer or manager in the biopharmaceutical and vaccines industry.

The integrity of the bioprocess ultimately determines the quality of the product in the biotherapeutics arena, and this book covers every stage including all technologies related...

'This is a blast of fresh air' Jonathan Clark, TLS'Thank goodness for Gottlieb' Daily Telegraph'A joy to read' EconomistThe author of the celebrated The Dream of Reason vividly explains the rise of modern thought from Descartes to RousseauIn a short period - from the early 1640s to the eve of the French Revolution - Descartes, Hobbes, Spinoza, Locke, Leibniz, and Hume all made their mark on Western thought. The Dream of Enlightenment tells their story and that of the birth of modern philosoph...

Learn how to safely sedate your dental patients and help control their anxiety with Sedation: A Guide to Patient Management, 6th Edition. Written by sedation expert Stanley Malamed, DDS, this concise guide combines essential theory with "how-to" technical instruction to help you master basic techniques in dental sedation and anxiety control. This new sixth edition also incorporates the latest guidelines from the ADA and the American Society of Anesthesiologists, along with vivid images of the...

How lessons from kindergarten can help everyone develop the creative thinking skills needed to thrive in today's society. In kindergartens these days, children spend more time with math worksheets and phonics flashcards than building blocks and finger paint. Kindergarten is becoming more like the rest of school.

In Lifelong Kindergarten, learning expert Mitchel Resnick argues for exactly the opposite: the rest of school (even the rest of life) should be more like kindergarten. To thrive in to...

Now is the time for conservation science—a mission-oriented scientific enterprise that seeks to protect nature, including Earth’s animals, plants, and ecosystems, in the face of unprecedented human demands upon the planet. Conservation scientists apply principles from ecology, population genetics, economics, political science, and other natural and social sciences to manage and preserve nature. The focus of this textbook is first and foremost on protecting nature and especially Earth’s ...

Understanding the earth’s climate system has never been more crucial.

At a time when the evidence is stronger than ever that human activity is the primary cause for global climate change, Ruddiman's breakthrough text provides a thorough and multi-disciplinary introduction to the earth’s climate. It offers a clear, engaging, objective portrait of the current state of climate science, including compelling recent findings on global warming and important advances in understanding past climates.

Cambridge English Proficiency 1 for updated exam (commencing March 2013) contains four complete and authentic examination papers for Cambridge English Proficiency, also known as Cambridge Certificate of Proficiency in English (CPE).

A full-color introduction to the basics of HTML and CSS from the publishers of Wrox! Every day, more and more people want to learn some HTML and CSS. Joining the professional web designers and programmers are new audiences who need to know a little bit of code at work (update a content management system or e-commerce store) and those who want to make their personal blogs more attractive. Many books teaching HTML and CSS are dry and only written for those who want to become programmers, which ...